THE PHOSPHATIDYLGLYCEROL PHOSPHATE SYNTHASE PGSA UTILIZES A TRIFURCATED AMPHIPATHIC CAVITY FOR CATALYSIS AT THE MEMBRANE-CYTOSOL INTERFACE

The phosphatidylglycerol phosphate synthase PgsA utilizes a trifurcated amphipathic cavity for catalysis at the membrane-cytosol interface

Phosphatidylglycerol is a crucial phospholipid found ubiquitously in biological membranes of prokaryotic and eukaryotic cells.The phosphatidylglycerol phosphate (PGP) synthase (PgsA), a membrane-embedded enzyme, catalyzes the primary reaction of phosphatidylglycerol biosynthesis.Mutations in pgsA frequently correlate with daptomycin resistance in S

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THE IMPORTANCE OF 99m-Tc DMSA RENAL SCINTIGRAPHY IN EVALUATION OF RENAL LESIONS IN CHILDREN WITH ACUTE PYELONEPHRITIS

"nUrinary tract infection (UTI) may lead to irreversible changes in renal parenchyma.Early diagnosis using scintigraphy with technetium-99m-labeled dimercaptosuccinic acid (DMSA) scan and early treatment may decrease or prevent development of renal parenchymal lesions.The aim of this study was to assess the occurrence of renal parenchymal lesi

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